List of GLP-1 Receptor Agonist

NOTE: so patient asked how to use TRULICITY (dulaglutide), and I remember it's a weekly dose, but how to use...not a clue :( Here is the answer :) By the way, they all belong to Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist

• TRULICITY (dulagluTIDE)
  
  
  
  (Available = 0.75mg or 1.5mg per 0.5ml)
• How to use from the manufacturer
• Dose
• 0.75mg SQ once weekly; may ↑ to 1.5mg
• Missed dose if < 3 days from next dose, wait until the next dose
• Mechanism of Action
• TRULICITY contains dulaglutide, which is a human GLP-1 receptor agonist with 90% amino acid sequence homology to endogenous human GLP-1 (7-37). Dulaglutide activates the GLP-1 receptor, a membrane-bound cell-surface receptor coupled to adenylyl cyclase in pancreatic beta cells. Dulaglutide increases intracellular cyclic AMP (cAMP) in beta cells leading to glucose-dependent insulin release. Dulaglutide also decreases glucagon secretion and slows gastric emptying.
• TRULICITY lowers fasting glucose and reduces postprandial glucose (PPG) concentrations in patients with type 2 diabetes mellitus. The reduction in fasting and postprandial glucose can be observed after a single dose.
• Storage
• Refrigerator or RT x 14 days
• BYDUREON (exenaTIDE) (Available = 2mg)
  
  
• How to use Bydureon
• Dose
• 2mg SQ once weekly
• TANZEUM (albigluTIDE)
• http://www.tanzeum.com/how-to-use.html