Hypotension - Pharmacist Letter *** to be cont. ***

NOTE: another CE quiz question on Pharmacist Letter :)

• Causes for hypotension
• Meds
• Parkinson
• BPH, including selective and non-selective alpha
• DOXAZOSIN (alpha1 adrenergic blocker, Available = 1, 2, 4, 8mg tab, Cardura XL = 4, 8mg) 
• TERAZOSIN (alpha1 adrenergic blocker, Available = 1, 2, 5, 10mg cap)
• TAMSULOSIN (alpha1 adrenergic blocker, Available = 0.4mg cap)
• ALFUZOSIN (UROXATRAL, alpha1 adrenergic blocker, Available = 10mg ER tab)
• RAPAFLO (siloDOSIN, alpha1 adrenergic blocker, Available = 4, 8mg cap with meal)
• Diuretics
• Treatment for hypotension
• Non-med
• Adequate fluid 
• Increase salt intake
• Med
• Fludrocortisone (Available = 0.1mg tab)
• Monitor
• Edema
• High BP
• ↓ potassium
• Midodrine (alpha1 agonist; Available = 2.5, 5, 10mg tab)
• Dose
• 10mg TID during daytime hours when patient is upright

Working with canker soresssss :( *** to be cont. ***

THOUGHTS: canker sores are always a nightmare especially when they are at the back of the throat AND on the lower lips :( Even a simple act of opening the mouth to speak raises the level of pain :( Well, life goes on, and work definitely goes on!!!

• ENTRESTO (SACUbiTRIL / valsartan) (Available = 24/26mg, 49/51mg, 97/103mg tab)
• NOTE: I saw this med ENTRESTO coming up refill too soon, and so I called the patient about it. However, I had no clue what this med is for!

Are EpiPEN all the same?

NOTE: another CE course brought me to the fountain of knowledge...indeed, I do not know if ALL EpiPEN are all the same?? Let's find out...


MYLAN brand ↓

 

LINEAGE brand ↓

IMPAX brand ↓

• 2 brands EpiPEN vs. ADRENAclick (intramuscular IM shot), and both have generic version
• Dose
• 0.3mg for >66 lb (30kg)
• 0.15mg for 33-66 lb (15-30kg)
• 0.01mg/kg
• May repeat dose in 5-15mins
• ADRENAclick vs. EpiPEN
• ADRENAclick
• 2 caps to remove
• Inject for 10 seconds
• Needle exposed from end red cap
• EpiPEN
• Blue cap to remove
• Inject for 3 seconds
• Needle never exposed

CE - diabetes drugs that also help CV outcome ... to be cont

NOTE: I'm just looking into satisfying my CE requirement (now I still need 18 units), and found this quiz question, which diabetes drugs also improve cardiovascular outcome? Looks like an interesting article!! So Let me summarize this article :)

• Improving CV outcomes
1. METFORMIN (Available = 
2. VICTOZA (liraglutide) (Available = 
3. JARdiance (EMPAglifloZIN) (Available =
4. ACTOS (pioGLITAZONE) (Available = 

List of GLP-1 Receptor Agonist

NOTE: so patient asked how to use TRULICITY (dulaglutide), and I remember it's a weekly dose, but how to use...not a clue :( Here is the answer :) By the way, they all belong to Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist

• TRULICITY (dulagluTIDE)
  
  
  
  (Available = 0.75mg or 1.5mg per 0.5ml)
• How to use from the manufacturer
• Dose
• 0.75mg SQ once weekly; may ↑ to 1.5mg
• Missed dose if < 3 days from next dose, wait until the next dose
• Mechanism of Action
• TRULICITY contains dulaglutide, which is a human GLP-1 receptor agonist with 90% amino acid sequence homology to endogenous human GLP-1 (7-37). Dulaglutide activates the GLP-1 receptor, a membrane-bound cell-surface receptor coupled to adenylyl cyclase in pancreatic beta cells. Dulaglutide increases intracellular cyclic AMP (cAMP) in beta cells leading to glucose-dependent insulin release. Dulaglutide also decreases glucagon secretion and slows gastric emptying.
• TRULICITY lowers fasting glucose and reduces postprandial glucose (PPG) concentrations in patients with type 2 diabetes mellitus. The reduction in fasting and postprandial glucose can be observed after a single dose.
• Storage
• Refrigerator or RT x 14 days
• BYDUREON (exenaTIDE) (Available = 2mg)
  
  
• How to use Bydureon
• Dose
• 2mg SQ once weekly
• TANZEUM (albigluTIDE)
• http://www.tanzeum.com/how-to-use.html