Let's go:
- What are the typical doses for ZENATANE (isotretinoin)?
- Available in 10, 20, 30, 40mg
- Weight base dose:
- Adult
- Manufactured: 0.5-1mg/kg/day in 2 divided dose x 15-20 weeks
- Alternative: 0.5mg/kg/day in 2 divided dose x 1 month ⟹ then ↑ 1mg/kg/day in 2 divided doses as tolerated until a cumulative dose of 120-150mg/kg
- Pediatric
- Manufactured: 0.5-1mg/kg/day in 2 divided dose x 1-20 weeks
- Alternative: 0.5mg/kg/day in 2 divided doses x 1 month ⟹ ↑ 1mg/kg/day in 2 divided doses as tolerated until a cumulative dose of 120-150mg/kg
- Monitoring:
- CBC with differential and platelet count
- Pregnancy test
- Lipids
- Liver function test
- Adverse reactions:
- ↑ serum triglycerides
- Warnings/precautions:
- Many many many...
- ZOMIG (zolmitriptan)
- Dose
- Nasal (available 2.5, 5mg)
- 2.5-5mg (may repeat in 2 hours; daily MAX = 10mg)
- Oral (available 2.5, 5mg PO & ODT)
- PO: 1.25-5mg (may repeat in 2 hours; daily MAX = 10mg)
- PO ODT: 2.5-5mg (may repeat in 2 hours; daily MAX = 10mg)
- KETOCONAZOLE topical
- Indications
- Cutaneous candidiasis
- Dandruff
- Seborrheic dermatitis
- Tinea corporis (general skin fungal infection), tinea crusis (jock itch), tinea pedis (athlete's foot)
- Protect from light
- How about feet? Still protect from light?
- FELBAMATE (anticonvulsant; available - suspension (600mg/5ml), tablets (400, 600mg)
- What is this???
- Dosing
- Inital = 1,200mg/day in 3-4 times daily (MAX = 3,600mg/day)
- Side effects
- Drowsy, dizzy, fatigue
- GRISEOFULVIN
- Microsize (Grifulvin V; available - not anymore)
- 500mg/day in single or divided doses
- Ultramicrosize (GRIS-PEG; available - 125, 250, 500mg)
- 375mg/day in single or divided doses
- SENSIPAR (cinacalcet; available = 30, 60, 90mg)
- Indications - hyperparathyrodism
- Dosing
- 30mg BID upto 90mg 3-4 times daily as necessary to normalize calcium levels
- Adverse reactions
- parasthesia (tingling sensation)
